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Sharma and Soman developed a novel group of structurally similar 3-aminocoumarin derivatives as DPP-4 inhibitors (106)
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Viral nsp12 could alter AA metabolism (especially of the branchedchain amino acids , BCAA), while nsp12, nsp7 , and nsp8 interactions with electron transport chain (ETC) and ribosomal proteins could potentially dysregulate mitochondrial respiration 39
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