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DSIP has been evaluated in experimental frameworks examining stress-induced changes in neuroendocrine signaling

& Nubler-Jung, K

Drug and alcohol abuse: Drug and alcohol abuse causes dementia by inducing neurotoxicity, brain inflammation, and vascular damage, which impair neural function and connectivity while also depleting essential nutrients like thiamine needed for cognitive health

Thus, cells have diverse mechanisms of mTORC1 activation for glutamine, and cancer cells efficiently utilize glutamine for mTORC1 pathway activation to drive unrestrained oncogenic growth

Trends in Biochemical Sciences , 26 (10), 597604