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doi: 10.1056/NEJMoa2413258 4 WangJ-YWangQ-WYangX-YYangWLiD-RJinJ-Yet al

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A candidate for a potential glutathione-scaffold residue was identified using the following selection criteria: The residue should be rather conserved in enzymatically active in contrast to inactive glutaredoxins and have a charged side chain to ensure a strong ionic glutathione interaction (Fig

Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer