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Research suggests that it protects against oxidative stress by scavenging free radicals, activating Nrf2/HO-1 signaling pathways, and preserving cellular redox homeostasis and mitochondrial function

Manipulating glutamine levels is challenging because glutamine is abundant in the body, as studies show minimal changes in plasma glutamine levels even after repeated high-dose supplementations [125]

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2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D (13, 15, 16), but the potential weight lowering efficacy for this class of molecules first seen in rodents was not confirmed in humans until clinical trials with the first long-acting GLP-1 analogue, liraglutide (12)

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