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Furthermore, the FDA has classified CJC-1295 as a Category 2 bulk drug substanceindicating it presents "significant safety risks" for compounding
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As diabetes is a major risk factor for CKD [67], specialized expert groups such as the Kidney Disease: Improving Global Outcomes (KDIGO) team, with the endorsement of both ADA and EASD, recommend that glycemic management for T2D patients with CKD should involve a combination of metformin and a SGLT-2 inhibitor as first-line therapy, with other drugs such as SUs considered only when additional therapies are needed for optimum glycemic control [68]
These compounds reduce oxidative stress catalysis by tightly binding ferric ions, ultimately inhibiting lipid peroxidation processes