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Some options, like Wegovy and Ozempic, contain semaglutide, which is a synthetic version of a naturally occurring hormone, glucagon-like peptide-1, or GLP-1

Results MAb 3F52 acts as a selective inhibitor of the GLP-1R The binding properties of mAb 3F52 to GLP-1R were characterized in a competition binding assay using 125 I-GLP-1(7-37)-OH as the tracer on cell membranes expressing the human GLP-1R

Importantly, when used alone, GLP-1 medications have a low risk of causing hypoglycemia (low blood sugar)

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This is a major, major turning point, both for the two companies vis-a-vis each other, but also I think really what sets Novo on the path to becoming Europe's dominant producer of Insulin and then ultimately the dominant producer of Insulin in the world