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Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans

B12 deficiency is a known concern with long-term GLP-1 therapy, particularly because many researchers are simultaneously reducing their caloric intake

Participants were monitored for 68 weeks (1.3 years) and given lifestyle interventions to adopt, encouraging 150 minutes per week of increased physical activity combined with a reduced calorie diet

A Focus on Diet and Nutrition Nutritional Counseling Some overweight and obese patients benefit from a professional assessment of their diet

GLP-1 has been proposed to have a role in lung protection (105), although this has primarily been described in rodents, where the GLP-1R is expressed at higher levels (87) and also in more diverse cell types (e.g., type 2 pneumocytes) than in humans (106)