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However, animal safety does not invariably ensure human safety

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As an endogenous regulatory peptide, DSIP functions as a neuromodulator within central nervous system signaling pathways, where it is studied as a modulator of hypothalamic and circadian rhythmassociated processes

[5] [7] At dosages exceeding 5 grams, there is a potential risk for more severe adverse effects, including renal dysfunction, blood toxicity, and neurological symptoms

Mural cells include vascular smooth muscle cells (VSMCs) surrounding big vessels and pericytes covering around 80% of smaller vessels