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For instance, the relaxation time can range from seconds in the brain, to minutes in the liver, and hours in the skin, with faster stress relaxation indicating increased viscoelasticity [138]

Four reasons GLP-1s affect sleep Circadian rhythm disruption GLP-1 receptors in the hypothalamus modulate GABA, orexin, and melatonin, shifting sleep-wake cycles Blood sugar fluctuations Your body adjusts to new overnight glucose patterns, disrupting sleep cycles during adaptation Physical side effects Night sweats, digestive discomfort, and nausea peak during the first 46 weeks and dose escalation periods Psychological factors Adjusting to a new relationship with food and body image can trigger anxiety or racing thoughts at night Free Resource Get Dr

GLP-1 receptor agonists like Ozempic may also have indirect effects on stress and mood