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BRP appears to act through brain pathways different from those targeted by GLP-1 drugs

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It targets three distinct receptors involved in metabolism, appetite, and energy homeostasis: Glucagon-like peptide-1 (GLP-1) receptor: The well-known target that influences insulin secretion, slows gastric emptying, and reduces appetite

The paper could unfold in two parts: - Part 1 aims to provide a cognitive framework of the situation including, first, an analysis of the context and processes that have led to a condition of structural crisis, and second, regeneration policies implemented by local and regional administrations