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Genetic polymorphisms in the DIO2 geneparticularly the common Thr92Ala varianthave been associated with altered enzymatic function and reduced intracellular T3 availability in key tissues, despite normal serum TSH and FT4 levels (1416, 29)

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Zheng J, Wittouck S, Salvetti E, Franz CMAP, Harris HMB, Mattarelli P et al (2020) A taxonomic note on the genus Lactobacillus : description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae

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Glutathione has been used topically, orally and parenterally in the management of dark skin