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In the SURMOUNT-1 trial, those on 15 mg of tirzepatide lost an average of 20.9% over 72 weeks

Cellular GSH synthesis is determined by the availability of the precursor amino acid cysteine as well as the rate-limiting enzyme glutamate cysteine ligase (GCL), which consists of a catalytic (GCLC) and a modifier (GCLM) subunit

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Clinical Takeaway: Personalised Nutritional and Lifestyle Support Understanding a patients MTHFR status allows for personalised interventions that address root biochemical dysfunctions rather than just symptoms

The key is knowing which tool to use