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Critical Appraisal of Included Publications Note that this appendix has not been copy-edited

Several limitations warrant consideration

No, semaglutide cannot be obtained from foods or supplements because it is a synthetic medication created through pharmaceutical engineering

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A 2023 review in the Journal of Clinical Endocrinology & Metabolism highlighted GLP-1 receptor agonists as promising adjunct therapies for women with PCOS and metabolic dysfunction, particularly when insulin resistance and obesity are present