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Furthermore, a proteomic study reported that small extracellular vesicles (sEVs) from fibroblasts contain TGF-1 and other differentially expressed proteins involved in fibroblast regulatory signalling pathways

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Similarly, CRISPR-Cas9 targeting of PCBP2 , an iron chaperone that prevents ferroptosis by delivering Fe 2+ to ferroportin, also increased sensitivity to palbociclib (Fig

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