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Visit the FDA MedWatch website or call 1-800-FDA-1088.

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The greatest barrier is cost even for insured patients, out-of-pocket expenses can be high, says Ryan

not more than once in 24 hours Onset: Effects typically begin within 3045 minutes Duration: Effects can last 612 hours Nausea mitigation strategies used in practice: Eat a low-fat meal approximately 1 hour before injection Consider prophylactic ondansetron (Zofran) 4 mg 30 minutes before, if nausea was problematic on prior doses Starting at 1 mg for the first dose to establish individual tolerance PT-141 is available by prescription only as Vyleesi (the brand-name autoinjector)