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Oxidation of dopamine and consequent quinone modification contribute to the vulnerability of dopaminergic neurons ( Mitochondrial Dysfunction Neuronal ATP formation depends on mitochondrial aerobic respiration, which normally produces hydrogen peroxide and superoxide radicals as byproducts during mitochondrial oxidative phosphorylation (5)

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Simultaneous application of cisplatin and erastin synergistically induces ferroptosis in colon and lung cancer cells ( Recently, the role of p53 biology in ferroptosis has received increasing interest for novel cancer treatments (Jiang et al., 2015)