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Direct head-to-head comparisons are not possible because the trials differed in duration, population and study design, but reporting outcomes side-by-side provides context

In critical sized segmental defect in a rat radius, application of inorganic bone matrix together with P-15 resulted in positive effect on bone healing, without any immunogenic features and disease transmission risk [133]

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This activation triggers a cascade of downstream signaling events leading to the activation of the PI3K-AKT/PKB and Ras-MAPK pathways