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More recent evidence indicates that sustained GIP receptor agonism in the presence of GLP-1 activation enhances insulin sensitivity and may preferentially reduce visceral adipose tissue

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Adding significant additional caloric restriction through keto in a person without significant fat stores creates genuine risk of lean mass loss, nutritional deficiency, and metabolic disruption

A minor deficit might result in weariness, weakness, and an overall impression of being weary and depressed

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