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However, total food intake was significantly reduced (Fig

Many articles in this study indicated the patients included had adequately followed these guidelines, some indicating patients fasting well beyond the recommended guidelines, and still noted either increased residual gastric contents, aspiration events, or other GI-related symptoms in the perioperative setting (Santos et al

Overall, these studies demonstrate that lipolysis signals a homeostatic response by providing ligands to nuclear receptors to regulate gene expression and thereby modulate cellular metabolism (Figure 3)

But the benefit is context-dependent

Clinical trials track predefined adverse events with strict reporting criteria