This discomfort typically resolves within minutes but varies significantly based on injection technique, individual pain sensitivity, and subcutaneous tissue composition
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Weight Loss Efficacy: What the Trials Show The most reliable data comes from the manufacturers pivotal trials, which are large, randomized, placebo-controlled and FDA-reviewed
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Patients may also have a harder time losing weight if they are on certain medications at the same time as a GLP-1 that can promote weight gain, such as certain antidepressants and beta blockers, Glickman says