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Studies have shown that methionine-enriched diets or acute methionine loads cause homocysteine to be exported from cells, leading to increased plasma homocysteine levels (Ueland and Refsum, 1989)

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The best way for healthy individuals to prevent a vitamin B12 overdose is to eat a well-rounded and healthy diet, incorporating foods high in B12 like organic animal meat, wild seafood, organic dairy products and eggs

Shortly after folic acid fortification was introduced, concerns were raised that higher intake might promote the progression of preneoplastic lesions in the colon (early cellular changes that could become cancer)