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This requires that the lens be transparent, a condition dependent on the highly regular organization of the cells of the lens and the high degree of short-range order of the proteins in the lens cytoplasm

LOH can thus shape not only the burden of SNVs and indels, but also SVs

e , Relative abundance of SLC25A39, GCLM and SLC25A40 transcripts in HEK-293T cells treated with BSO (1 mM) for the indicated days using quantitative reverse transcription PCR (RT-qPCR), normalized to transcripts of -ACTIN

This is the highest dose approved by the FDA

Less common but serious risks Pancreatitis (inflammation of the pancreas) has been reported in some cases