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Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving nitrofurantoin oral suspension [see Adverse Reactions (6)]

Clinical trials found that liraglutide (1.83 mg) effectively induced and sustained weight loss in people with obesity, including participants who also had weight-related conditions (e.g., high blood pressure or obstructive sleep apnea)

found that in sheep ovarian granulosa cells, LPS treatment suppresses GPX4 expression, resulting in lipid peroxide accumulation and decreased mitochondrial membrane potential, while restoration of GPX4 expression reverses LPS-induced ferroptosis (61)

In obesity, abnormal adipose metabolism transports large amounts of free fatty acids to the liver, increasing hepatic fat synthesis, decreasing fat breakdown, and ultimately causing hepatic steatosis

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