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Specifically, IL-4 promotes an anti-inflammatory phenotype by upregulating Arg1 [88], whereas IFN- induces a proinflammatory state, leading to the release of TNF- and IL-6 and the upregulation of MHC-II, which contributes to neuroinflammation [89]

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En investigaciones clnicas en humanos, se ha estudiado Cagrilintide por sus efectos en la reduccin del apetito, la modulacin de la ingesta energtica y la regulacin del peso corporal