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It modulates nitric oxide pathways to normalize lower esophageal sphincter function, reduces oxidative stress markers like malondialdehyde, and decreases inflammatory cytokine expression (TNF-, IL-6)
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The first author claims that this resulted in a balanced dataset inclusive of the sample countries and further states that the imputation of missing values based on variablespecific trend will not change the result and large number of observations will produce more stable estimated coefficients
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