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202 HSPs in radiotherapy resistance HSPs are also implicated in resistance to radiotherapy

Although most cells can catalyze GSH synthesis, rates of GSH production may be inadequate or insufficient to maintain cellular concentrations of GSH during disease or toxic states 39

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According to NICE Clinical Knowledge Summaries, B12 supplementation for confirmed deficiency should follow established protocols, but routine monitoring of B12 levels after treatment initiation is not always necessary unless clinical response is inadequate