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The retatrutide Phase 2 obesity trial , published in the New England Journal of Medicine, demonstrated weight loss of up to 24.2% at the 12mg dose after just 48 weeks
Both medications suppress appetite, both cause gastrointestinal side effects that can lead to dehydration, and both produce weight loss that stresses the musculoskeletal system
Both drugs, particularly higher doses of tirzepatide, increased gastrointestinal adverse events
High-dose oral b12 protocols Oral b12 can overcome absorption issues through mass action
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