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To test this, we treated Hs 578T cells with amino-oxyacetic acid (AOAA) and I3MT-3, pharmacological inhibitors of endogenous H 2 S-producing enzymes, and observed no decrease in NRF2 expression (Fig

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The exogenous origins of ROS are exposure to ionizing radiation (IR), ultraviolet (UV) radiation, biological organisms, pollutants, food, alcohol, and tobacco [33, 34]

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