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Upon tight binding to gastric epithelial cells, adhesins employ a range of effector proteins, including vacuolating cytotoxin A (VacA), cytotoxin-associated gene A (CagA), and cytotoxin-associated gene L protein (CagL), to manipulate host cell signaling and alter the behavior of gastric epithelial cells, thus promoting long-term colonization (Salama et al., 2013)

The production of diverse mediators by the airway epithelium is a crucial aspect of innate immunity and the inflammatory response

That figure reflects any measurable reduction rather than a defined clinical outcome so it should be read in that context

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Ryu JK, Kim SJ, Rah SH, Kang JI, Jung HE, Lee D, Lee HK, Lee JO, Park BS, Yoon TY, Kim HM (2017) Reconstruction of LPS transfer cascade reveals structural determinants within LBP, CD14, and TLR4-MD2 for efficient LPS recognition and transfer