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Interestingly, p38 exhibits context-dependent effects: under physiological conditions (e.g., exercise), p38 promotes mitochondrial biogenesis and fiber-type remodeling (Vainshtein and Sandri, 2020)

[DOI] [PubMed] [Google Scholar] 28.Fernndez-Baares F., Hinojosa J., Snchez-Lombraa J.L., Navarro E., MartnezSalmern J.F., Garca-Pugs A., Gonzlez-Huix F., Riera J., Gonzlez-Lara V., Domnguez-Abascal F., et al

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Glucosamine is an endogenous amino sugar that serves as a fundamental building block for glycosaminoglycans (GAGs), the water-trapping molecules that give cartilage its spongy, shock-absorbing quality