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The exception involves individuals with specific genetic variants in the MTHFR, MTR, or MTRR genes that impair B12 metabolism

Without enough NAD, your body's ability to create energy slows down, making it harder for your cells to do their jobs. On top of metabolism, NAD can also be an anti-ageing boost as well

A complete medical history assessing for gut inflammation, celiac disease, GERD, recent nitric oxide use in surgery, and genetic factors like MTHFR should trigger a closer look at B12 adequacy even with a normal homocysteine (HCY) plasma test

While some individuals may require weekly injections initially to address severe deficiency, the frequency often decreases over time as B12 levels stabilize

The CDC highlights preventable infections caused by unsafe vial handling