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They help people lose weight by working in both the gut and the brain, acting on digestion, insulin and appetite, helping quiet cravings and what users describe as food noise. So named for the GLP-1 hormone they mimic, the medicines have also shown success in cardiovascular disease, heart failure, sleep apnea and kidney disease

Extensive anaerobic subculturing of human feces identified no single commensal capable of l-carnitineTMA transformation, multiple community members that converted l-carnitine to BB, and only 1 Clostridiales bacterium, Emergencia timonensis , that converted BB to TMA

10.1105/tpc.12.10.1939 35 MontezanoA

This case highlights the diagnostic challenges posed by concurrent bacterial and viral CNS infections and the value of rapid molecular diagnostics, including NAAT and multiplex PCR, for early pathogen identification and targeted therapy

However, BDNF is suggested to show anti-epileptic effects in other studies (Cifelli et al