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Patients with kidney impairment must be cautious with magnesium supplementation, as compromised renal function reduces magnesium excretion

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Switching requires new titration (812 weeks), may temporarily restart GI side effects, and will need insurance reauthorization but the mechanism shift from dual to triple agonism may produce meaningful additional weight loss

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid- levels in APP/PS1 transgenic mice

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