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FDA Criteria Explained Contrave is an FDA-approved prescription weight loss medication, indicated for adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition like type 2 diabetes, high blood pressure, or high cholesterol

no controlled trial supports it for gut health or leaky gut

(2022) highlighted that neurological and neuropsychiatric symptoms, including brain fog, are more commonly reported in women [24], while Asadi-Pooya et al

These medications also target the endocrine system to reduce insulin resistance, lower fasting glucose levels, and signal that the body is no longer in crisis mode

Additional contributing factors include reduced food and fluid intake