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Nutrients 11(9):2073

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Cereb Cortex 20:684-693

In the latest Cochrane review of 12 placebo-controlled trials, supplementation with folic acid, vitamin B 6 , and vitamin B 12 either alone or in combination did not affect the risk for myocardial infarction and was associated with only a very small reduction in risk for stroke (RR, 0.90