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No controlled trial has measured its skin effects or established a reliable results timeline

While more research is still needed to see how well this works in humans, early studies are promising

In studies, its shown promising improvements in skin texture and appearance with usage over weeks and exhibited similar effectiveness to hydroquinone

Side Effect Comparison Both agents share gastrointestinal side effects as their primary tolerability issue

For example, CAN often presents with resting tachycardia and orthostatic hypotension, so nonpharmacologic strategies (such as adequate salt intake and physical activities and avoidance of medicine-related hypotension) and pharmacologic strategies (such as midodrine and droxidopa) should be considered to minimize postural symptoms rather than to restore normotension