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Pooled results from seven non-pharmacological trials were associated with a statistically significant 48% relative reduction of TIN risk with low heterogeneity and the pooled results from six pharmacological trials were associated with a significant 20% relative reduction of TIN risk with moderate heterogeneity
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Additionally, a cohort study of 371,463 individuals provided genetic evidence that varying alcohol intake levels are linked to a persistent, nonlinear increase in the risk of hypertension and coronary artery disease
doi: 10.1038/s41588-018-0099-7 42
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