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Tom Brunner: Thank you, David, what a fascinating talk about your amazing research

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This raises the possibility that the DA synthesized by - and -cells also locally activates -cell D2R to inhibit SST secretion and thus removes SST-mediated inhibition of insulin and glucagon release 32,91,93,94,95,96,97,98

Substantial evidence has been accumulated that reveals metabolic defects in both the peripheral and central tissue of patients with SZ (see reviews by Skosnik and Yao, 2003