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NNMT is expressed abundantly in adipose tissue, where it has been associated with fat cell size and lipid storage dynamics

No validated human pharmacokinetics A human half-life, bioavailability, tissue distribution, metabolic pathway and exposure-response relationship have not been established through a published clinical programme

However, copper peptides should not be mixed directly with high-dose vitamin C or strong AHA/BHA formulations in the same application step, as these can chelate copper ions and reduce efficacy

The higher-exposure group showed less body-weight and fat-mass gain than controls

All compounds at peak coordinated activity