glutathione metabolism disorder - an overview Apoptosis and glutathione: beyond an

glutathione metabolism disorder

glutathione metabolism disorder - an overview Apoptosis and glutathione: beyond an

Name: glutathione metabolism disorder - an overview Apoptosis and glutathione: beyond an
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Description

& Ramezani, A

Glutathione synthesis occurs in two ATP-dependent steps catalyzed by the enzymes gamma-glutamylcysteine ligase (GCL, the rate-limiting step) and glutathione synthetase [2]

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Gclc is required for T cell-independent and -dependent B cell immune responses Next, we aimed to understand how the metabolic perturbations caused by B cell-specific Gclc ablation impinge on immune responses and in particular how the impaired mitochondrial metabolism affects the antibody response