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Investigating cardiovascular health outcomes is critical, as weight loss may reduce long-term risks of hypertension, atherosclerosis, and insulin resistance

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Gene ontology analysis of the gene set from cluster 1 revealed a significant enrichment of gene ontology terms associated with critical cellular processes, including dopaminergic synaptic transmission, prepulse inhibition and enriched biological processes (like locomotor behaviour and drug response) (Extended Data Fig

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Additionally, curcumin has shown strong anti-inflammatory properties (229)