Silymarin has been reported to act as an antioxidant by reducing free radical production and lipid peroxidation, function as a toxin blocker by inhibiting the binding of toxins to the hepatocyte cell membrane receptors (Papackova et al., 2018)
FDA procedurally removed it from Category 2 in April 2026 after nominators withdrew their submissions and referred it to the Pharmacy Compounding Advisory Committee, which is scheduled to review it on July 23-24, 2026 for possible inclusion on the approved 503A bulks list
Changing the dose without supervision may increase the risk of side effects, poor response, hormone-related concerns, or unsafe stacking with other products
But if it does not work for you, then there is another option try it with a small amount of healthy fat, such as some slices of avocado or a handful of nuts
It may also help protect the cells that maintain the skin barrier, which could possibly decrease water loss and keep your skin looking hydrated and youthful