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The authors highlighted mechanism-based combination strategiessuch as pairing HDACis with DNA-damaging agents, kinase inhibitors, immune checkpoint inhibitors, or proteasome inhibitorsthat can enhance antitumor responses and overcome resistance (209)

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Err-KO Alleviated Neuroinflammation in SABD The serum markers related to brain damage, neuron specific enolase (NSE), and S100 calcium-binding protein B (S100) are downregulated in Err-KO-SABD mice compared to WT-SABD mice (Fig