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Doxycycline-resistant MCF7 cells show an increase in CSC markers, but not in functional CSC activity, as measured using mammosphere assays, proliferation and cell migration ALDH activity and CD44/CD24 levels are routinely used as typical markers to identify breast CSCs [17]

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Lack of Human Clinical Trials : No approved human clinical trials exist for BPC-157, and benefit or safety data are derived exclusively from animal models

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On the other hand, CJC-1295 is a growth hormone-releasing hormone analog that extends the half-life of endogenous GHRH, leading to a more sustained release of GH over time