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Ren Y, Chen Y, Zheng W, et al

Up to 80% of cirrhosis patients report poor sleep quality, as evidenced by Pittsburgh Sleep Quality Index (PSQI) scores exceeding 5 (ChildTurcottePugh [CTP] A: 16.9%, CTP B: 26.5%, and CTP C: 56.6%), and around 16 to 52% suffer from excessive daytime sleepiness (EDS), reflected by Epworth Sleepiness Scale (ESS) scores over 10 (CTP A: 17.6%, CTP B: 29.7%, CTP C: 52.8%) ( Insomnia, defined as difficulty initiating or maintaining sleep, is chiefly diagnosed through patient-reported symptoms

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Each peptide is synthesized from pharmaceutical-grade amino acids, purified, freeze-dried, and packaged in sterile conditions for consistent particle size and solubility

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