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In addition to activating NRF2 and inducing antioxidant enzymes, some NRF2 activators may also affect other signaling pathways, potentially interfering with related biological processes

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Gastric acidity, reflux, and other gastrointestinal symptoms Three articles indicated that there was also no significant difference in reflux symptoms experienced by patients taking GLP-1 RAs versus those who were not (Santos et al

This has led to the understanding that obesity is a chronic condition requiring ongoing management, similar to hypertension or diabetes

doi: 10.1093/jn/132.6.1214 21