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Another exciting avenue is the development of small-molecule GLP-1RAs, designed for oral delivery

These are usually mild and temporary

The oxidative stress state was shown to be reduced after Dula pretreatment (50, 100, and 150 g/kg), as evidenced by the rise in SOD, TAC, and GSH concentrations and the fall in MDA levels, these results were based to the previous study which concurs with our findings (Wang et al

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This may result from improved metabolic regulation due to DPP-4 inhibition, reduced glucagon levels, and enhanced insulin activity