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The dynamics of this first wave of offpatent entrants will be shaped not just by the cost of development, but also by regulatory classification, privatemarket affordability, and innovators ability to segment the market with second brands and nextgeneration therapies

Remove from the stove

Fat cells produce oestrogen through the conversion of androgens, and they also influence levels of sex hormone-binding globulin (SHBG), which affects the availability of reproductive hormones

The rapidity in growth and the aggressive clinical behaviour of the tumour can be deceptive and hence lack of familiarity with the clinical characteristics of the tumour may often lead to an erroneous diagnosis of malignancy

Pediatr Neurol 2021;119:15-21