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"Both semaglutide and tirzepatide are well-known for their effects on weight loss and blood sugar control, but our study suggests they may also offer substantial benefits to patients with obesity and type 2 diabetes by reducing adverse heart failure outcomes." Despite promising results from existing randomized controlled trials of semaglutide and tirzepatide in those with obesity-related HFpEF, regulatory authorities and professional societies have not approved or endorsed the use of these drugs for HFpEF, due in part to the studies relatively small sample sizes and unknown generalizability

ND, not determined

Sukenik S, Buskila D, Neumann L, Kleiner-Baumgarten A, Zimlichman S, Horowitz J: Sulphur bath and mud pack treatment for rheumatoid arthritis at the Dead Sea area

A North Carolina patient was hospitalized for 72 hours due to severe vomiting and dehydration after a virtual prescribing service instructed her to double her dose of compounded semaglutide

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