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This multi-receptor activation enables: GLP-1R activation enhances glucose-dependent insulin secretion and reduces appetite through hypothalamic signaling GIPR activation (highest potency: EC50 0.0643 nM) promotes insulin secretion and modulates lipid metabolism GCGR activation (EC50 5.79 nM) increases energy expenditure and promotes hepatic fat oxidation Combined receptor engagement produces dose-dependent reductions in body weight and improvements in glycemic control Research demonstrates that GLP3s balanced activation across three receptors produces superior metabolic effects compared to single or dual agonists, with phase 2 trials showing up to 24.2% weight reduction in 48 weeks[2]

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It can be a slow IV push or an IV infusion

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Biogenic Foods Tesamorelin & Ipamorelin - 12mg/2mg *Phoenix Blend* - Research Peptide SKU: tes/ipa-12mg/2mg Weight: 2.00 Ounces Description Description CAS Number: N/A (research blend) Molecular Formula: N/A (research blend) Molecular Weight: N/A (research blend) Form: Lyophilized Powder Quantity: 12mg/2mg vial Purity: 98% (HPLC Verified) Product Overview: Tesamorelin/Ipamorelin (12mg/2mg) is a synergistic peptide blend pairing Tesamorelin, a synthetic growth hormonereleasing hormone (GHRH) analog, with Ipamorelin, a selective growth hormone secretagogue receptor (GHSR) agonist